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Lewis, The effect of ascorbate and -tocopherol supplementation in vitro on DNA integrity and hydrogen peroxide-induced DNA damage in human spermatozoa, Mutagenesis, 1999, doi: 10.1093/mutage/14.5.505

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For example, decreased sodium excretion (increasing levels) results in water retention and a condition known as volume overload, which causes swelling of tissues (edema)

Peter Attia, a longevity physician, discusses NAD+ precursors: "While evidence is emerging, NAD+ boosting shows promise for mitochondrial health and longevity, though IV might not be optimalprecursors like NMN could be better."[33][20] On combinations, he cautions on long-term data but notes potential for metabolic disorders